Breast Cancer Reserach Studies at John Stoddard Cancer Center

UnityPoint Clinic Urgent Care - Altoona

00 Patients
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UnityPoint Clinic Urgent Care - Ingersoll

07 Patients
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Urgent Care - Ankeny

03 Patients
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Urgent Care - Lakeview

01 Patients
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Urgent Care - Merle Hay

04 Patients
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Urgent Care - Southglen

00 Patients
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Urgent Care - Urbandale

02 Patients
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Breast Cancer Research Studies

TRIPLE NEGATIVE

BR003: A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer.

 

WO39391: A Phase III, Randomized, Open-Label Study Comparing Atezolizumab (Anti-PD-L1 Antibody) in Combination with Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone in Patients with Operable Triple-Negative Breast Cancer

 

NODE+ / HIGH RISK NODE - / HER2-

A011502: A Randomized Phase III Double-Blinded Placebo-Controlled Trial of Aspirin as Adjuvant Therapy for Node-Positive HER2 Negative Breast Cancer: The ABC Trial.

 

INFLAMMATORY

S1706: A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy alone for Inflammatory Breast Cancer

 

DCIS

AFT-25: Comparison of Operative to Monitoring and Endocrine Therapy (COMET) Trial for Low Risk DCIS: A Phase III Prospective Randomized Trial

 

METASTATIC

A171601: A Phase II Trial Assessing the tolerability of Palbociclib in Combination with Letrozole or Fulvestrant in Patients aged 70 and older with Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer

 

BR004: A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

 

POST NEOADJUVANT

A011202: A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (CT1-3N1) who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy.

 

B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy.

 

EA1131: A Randomized Phase III Post-Operative Trial of Platinum-Based Chemotherapy Vs. Capecitabine in Patients with Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy.

 

S1418: A Randomized Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer with ≥ 1cm Residual Invasive Cancer or Positive Lymph Nodes (ypN+) After Neoadjuvant Chemotherapy.

 

CANCER CONTROL

A011404: Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer

 

A221505: Phase III Randomized Trial of Hypofractionated Post Mastectomy Radiation with Breast Reconstruction

 

CC004: Phase II Double Blind Dose-Finding Trial of Bupropion Versus Placebo for Sexual Desire in Women with Breast or Gynecologic Cancer

 

WF-97116: A Phase 3 Placebo-Controlled Clinical Trial of Donepezil in Chemotherapy Exposed Breast Cancer Survivors with Cognitive Impairment

 

CANCER CARE DELIVERY RESEARCH

S1415CD: "TrACER": Trial Assessing CSF prescribing Effectiveness and Risk