Clinical Research | UnityPoint Health - Meriter

Clinical Research

Clinical research is a vital component of today's ever-evolving healthcare field, allowing physicians and providers to break new ground and giving patients new alternatives to lifesaving treatment options. UnityPoint Health – Meriter regularly participates in clinical research — giving us the opportunity to test the safety and effectiveness of new treatments such as medicines, medical procedures and devices.

Patients volunteer to participate in clinical research because they hope it will benefit them and because they want to contribute to a research effort that helps patients in the future. Whether the outcome of clinical research is beneficial or disappointing, patients involved in clinical research are helping to find new and better treatments.

If you are interested in learning more about a specific research project, please contact the person listed.

Heart & Vascular

  • C1973-204 - A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 2 Study Evaluating the Safetey and Efficacy of Different Doses of IW-1973 over 12 Weeks in Patients with Heart Failure with Preserved Ejection Fraction. 

  • Clear Outcomes - A randomized, Double-Blind, Placebo-Controlled Study to Access the Effects of Bempedoic Acid (ETC-1002) on the Occurrence of Major Cardiovascular Events in Patients with, or at High Risk for Cardiovascular Disease who are Statin Intolerant

  • EMPEROR-Preserved - A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with preserved Ejection Fraction (HFpEF). 

  • LSS 4-Site - The Longitudinal Surveillance Study of the 4-SITE

  • Maverick-HCM - A Randomized, Double-blind, Placebo-controlled, Concentration-guided, Exploratory Study of Mavacamten (MYK-461) in Patients with Symptomatic Non-obstructive Hypertrophic Cardiomypathy

  • Orion 4 - A double-blind, randomized, placebo controlled trial assessing the effects of inclisiran on clinical outcomes among people with atherosclerotic cardiovascular disease.

  • PROMINENT - Pemafibrate to reduce cardiovascular outcomes by reducing triglycerides in diabetes patients. 

  • SAFE-DBC - A Prospective, Multicenter, Single Arm, Real-World Registry Assessing the Clinical Use of the Lutonix® 035 Drug Coated Balloon Catheter in Arteries of the Superficial Femoral Artery (SFA) and Popliteal Artery (PA)

  • VOYAGER - Vascular Outcomes study of Asa along with rivaroxaban in Endovascular or surgical limb Revascularization for peripheral artery disease (PAD)

Women's Health, including Maternal, Prenatal Health and Newborns

  • 2017-003 - Remote Patient Monitoring: Telehealth for management of postpartum hypertension

  • 2018-006 - Angiotensin 2 receptor expression/activation in endothelial cells in preeclampsia

  • 2019-017 - Pre-eclampsia: Inflammatory Cytokine Profile Changes with in Vitro Exposure to Vitamin C and Brachial Artery Fluid Dynamic