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How to Prepare for a COVID-19 Vaccine

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A health care worker giving a patient a COVID-19 vaccine; How to Prepare for a COVID-19 Vaccine

Once you become eligible and your COVID-19 vaccine is scheduled, you might wonder, “What should I expect from my vaccine experience?” Dr. Stephen Rinderknecht, chair of the UnityPoint Clinic Vaccine Committee, walks through the process to help you feel prepared before, during and after your COVID-19 vaccine.

What to Expect Before Your COVID-19 Vaccine

Do I need a COVID-19 Test Before My Vaccine? 

No, you don’t need to get a COVID-19 test before your scheduled vaccination. However, if you’re not feeling well, it’s a good idea to pause and check with your doctor before proceeding.

As with most other vaccines, it’s OK to roll up your sleeve for the COVID-19 vaccine if you’re just mildly ill from things like a cold, ear infections or even mild diarrhea. Normally, a low-grade fever during a vaccine isn’t a problem either. However, with the current pandemic, any fever without explanation needs to be approached with caution. If it turns out you do have COVID-19, you wouldn’t want to put others at risk leaving your home.

Also, if you happen to get COVID-19 after your first COVID-19 vaccine dose but before the second, delay the second dose until after you’re feeling better and the isolation period recommended for COVID-19 is over.

Can I Get a COVID-19 Vaccine at the Same Time as Another Vaccine?

No, the CDC recommends you get the vaccine without any other vaccines. You should also keep 14 days on either side of your COVID-19 vaccine. For example, if you get another vaccine (like the flu shot), you need to wait 14 days to get the COVID-19 vaccine. And, if you need a vaccine after your COVID-19 vaccine, it’s recommended you wait 14 days to do so.

Can I Take Medication Before the Vaccine to Lessen Side Effects?

It’s not recommended to take medication before your vaccine to lessen side effects. However, if you do notice any side effects (like a sore arm, headache or fever) following your vaccine, it’s OK to take an over-the-counter medication like acetaminophen to manage any discomfort.

What Should I Bring to My COVID-19 Vaccine Appointment?

It’s a good idea to bring your insurance documents, if available, and a form of identification to your appointment. Some vaccination sites may also request to see proof of employment if you’re eligible for vaccination due to your employment status.

Also, before you leave home, think about what you’re wearing. Make sure the care team can easily access your upper arm to administer the vaccine.

What to Expect During Your COVID-19 Vaccine 

How Long Will It Take to Get My COVID-19 Vaccine? 

That all depends on where you get your vaccine. If it’s staffed adequately and the workflow is pinned down, it should only take a short time to get you back to your daily duties.

Where Will the Vaccine be Administered?

Usually, the vaccine is given in the upper arm – specifically the deltoid muscle. The thigh is another option, but it’s rarely used. These vaccine locations are the safest places to receive an intramuscular injection because they have very few nerves and blood vessels. Most vaccines are given in the arm muscle because it allows the medication to be absorbed into the bloodstream very quickly.

You can receive your second COVID-19 vaccine in either arm.

What’s the Needle Like for the COVID-19 Vaccine?

The needle used for the COVID-19 vaccine is the exact same size as what’s used for other routine vaccines – like the flu shot. It usually measures just one inch. Like getting the flu shot, the injection of the COVID-19 vaccine should cause little or no pain.

If you tend to tense up during vaccines, take a moment before your COVID-19 vaccine to take a deep breath and relax your arm. That might help reduce the soreness at the injection site.

What Will I Feel When the Vaccine Goes into My Arm?

Although these vaccines require subzero temperatures for storage, they are completely thawed before being given to you. So, you shouldn’t feel a cold sensation when it goes in.

Can I Leave and/or Drive Away Immediately After My Vaccine?

An observation period of 15 minutes is recommended. The reason – any severe reactions usually occur 15 to 30 minutes after the COVID-19 vaccine. A severe allergic reaction, called anaphylaxis, has been very rarely reported. In fact, in the first approximately six million doses, 31 cases of anaphylaxis occurred.

If you have a history of any anaphylactic reaction, you should be observed for 30 minutes. If you experience any allergic reaction to the first dose of the COVID-19 vaccine, don’t get a second dose.

What is the Card People are Getting at Their Vaccine?

During your first dose of the COVID-19 vaccine, you should get a COVID-19 vaccination record. It usually comes in the form of a card or printout. It contains information on which vaccine you received and the date. This card is for your personal use and should be saved for your records. Keep the card handy, you’ll want to bring it with you for your second dose.

Your vaccine information is also entered into your state’s electronic vaccine information system. Often, your state’s system is linked to your doctor’s office – so your vaccine record may also appear in your medical records. For UnityPoint Health, it’ll be available to you in your MyUnityPoint account.

While some are celebrating their vaccine by posting a picture of themselves with their COVID-19 vaccination record card, it’s not a good idea. The Federal Trade Commission says it’s an invitation for identity theft.

What to Expect After Your COVID-19 Vaccine 

What Side Effects Can I Expect? 

Remember, side effects are your body’s natural response to the COVID-19 vaccine. It’s a good sign your immune system is starting to kick in to keep you protected. If you don’t experience any side effects, that’s OK, too. According to the CDC, common responses to the vaccine include arm soreness, tiredness, headache, muscle pain, chills and/or fever.

Interestingly, younger people report feeling more of the side effects than other age groups.

How Long After the COVID-19 Vaccine Can You Have Side Effects?

The normal immune system reaction usually begins the day after your vaccine but can start up to three days out. If you notice any side effects, they should only last for about a day.

Many people are hesitant about the vaccine because of uncertainty regarding long-term side effects. However, experience tells us side effects appearing beyond two months after the vaccination are extremely rare.

How Do I Report Vaccine Side Effects to the CDC?

V-safe is a new program providing near real-time information on potential side effects from the COVID-19 vaccine. Participation is voluntary but recommended. The program is designed and operated by the CDC and FDA and runs through smart phones. You’ll receive information on how to register when you get your first vaccine.

After registering, you receive a text message daily for seven days, then weekly for six weeks. You’ll also get a message at month three, six and 12. The messages ask basic questions about your health and how you’re feeling. It’ll take just a couple of minutes to respond. You can also add open comments.

This program is designed to help track possible vaccine side effects that might not have shown up in the original studies.

Why is the Second Dose of the Vaccine so Important?

Early data shows there’s some protection from COVID-19 after the first dose, but the second dose provides a much better immune response. After receiving your first dose, you’ll receive instructions on when and how to schedule your second dose. About two weeks after second dose, you’ll reach the highest protection against COVID-19 at about 95 percent.

It's important the second dose only be given after the recommended time interval designated by each vaccine maker. Your second dose of the Pfizer vaccine should be at least 21 days after the first dose. Your second dose of the Moderna vaccine should be at least 28 days after your first dose.

Will the Side Effects be the Same After Both Vaccine Doses?

It’s a common experience to notice a stronger reaction to the second dose of the vaccine than the first. This phenomenon is typical for most multi-dose vaccines. The types of side effects are the same – arm soreness, tiredness, headache, muscle pain, chills and/or fever.

Why Do I Still Need to Wear my Mask?

After receiving the COVID-19 vaccine, it's still important to follow all the guidelines we've come to know during the pandemic: wear a mask, social distance, wash your hands and stay home when you're sick. There are a few reasons, but primarily, scientists are still figuring out if the vaccine will impact asymptomatic (someone has the infection but no symptoms) spread of COVID-19. In other words, experts are trying to figure out if vaccinated people can still carry and spread the virus, even though they don’t feel sick from the virus themselves.

For more information, please check out our COVID-19 vaccine page.