Currently Enrolling Clinical Studies

Adult Clinical Research Studies

Heart and Vascular Research

ANTHEM- Heart Failure

Autonomic Regulation Therapy To Enhance Myocardial Function and Reduce Progression of Heart Failure with Reduced Ejection Fraction

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

BAYER - Heart Failure

A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Finerenone on Morbidity and Mortality in Participants with Heart Failure (NYHA II-IV) and Left Ventricular Ejection Fraction ≥ 40% (LVEF ≥ 40%)

For more information please contact Debra at 309-672-3194. The Principal Investigator for this study is Dr. Alexander Adler.

BMAD - Heart Failure

Benefits of Microcor µCOR™ in Ambulatory Decompensated Heart Failure

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

DAPA - Heart Failure

A Multicenter, Double-blind, Placebo-controlled, Randomized Withdrawal, Parallel-Group Study of Patiromer for the Management of Hyperkalemia in Subject Receiving Renin-Angiotensin-Aldosterone System Inhibitor (RAASi) Medications for the Treatment of Heart Failure. 

For more information please contact Debra at 309-672-3194. The Principal Investigator for this study is Dr. Alexander Adler.

NODE - Paroxysmal Supraventricular Tachycardia

Multi-Centre, Multi-National, Open Label, Safety Study of Etripamil Nasal Spray for Patients with Paroxysmal Supraventricular Tachycardia

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Adel Mina.

PARAGLIDE - Heart Failure

A multicenter, randomized, double-blind, double-dummy, parallel group, active controlled 8-week study to evaluate the effect of sacubitril/valsartan (LCZ696) versus valsartan on changes in NT-proBNP and safety and tolerability of in hospital initiation of LCZ696 compared to valsartan in HFpEF patients with acute decompensated heart failure (ADHF) who have been stabilized during hospitalization.

For more information please contact  Debra at 309-672-3194. The Principal Investigator for this study is Dr. Alexander Adler.

SPIRRIT - Heart Failure

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

scPharma - Heart Failure

A Multicenter, Randomized, Open Label, Controlled Study Evaluating the Effectiveness and Safety of Furoscix On-Body Infusor vs Continued Medical Therapy for Worsening Heart Failure

For more information please contact Teresa at 309-672-4808. The Principal Investigator for this study is Dr. Alexander Adler.

TRANSFORM - Heart Failure

ToRsemide compArisoN with furoSemide FOR Management of Heart Failure

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

Diabetes Research

ARISE - Diabetic Cardiomyopathy

A Multicenter, Randomized, Placebo-Controlled Study to Evaluate the Safety and Efficacy of AT-001 in Patients with Diabetic Cardiomyopathy / Stage B Heart Failure at High Risk of Progression to Overt Heart Failure (Stage C Heart Failure)   

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. David Trachtenbarg.

Gastrointestinal Research

RiCoDIFy - C-Difficile

Phase 3, randomized, double-blind, active controlled study to compare the efficacy and safety of ridinilazole (200 mg, bid) for 10 days with vancomycin (125 mg, qid) for 10 days in the treatment of Clostridium difficile infection (CDI).

For more information please contact Teresa at 309-672-3118. The Principal Investigator for this study is Dr. David Trachtenbarg.

Oncology Research

SEERPRO - Cancer

A Prospective Blood Sample Collection Study to Evaluate a Panel of Protein-based Biomarkers  

For more information please contact Debra at 309-672-3194. The Principal Investigator for this study is Dr. Candace Correa.

Respiratory Research

RESOLUTE – COPD

A Multicenter, Randomized, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Phase 3 Study to Evaluate the Efficacy and Safety of Benralizumab 100 mg in Patients with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) with a History of Frequent COPD Exacerbations and Elevated Peripheral Blood Eosinophils.

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Ravindra Kashyap.

COVID-19 Research

Edesa – COVID-19

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC vs. Placebo + SOC in Adult Hospitalized Patients with COVID-19

For more information please contact Debra at 309-672-3194. The Principal Investigator for this study is Dr. Ravindra Kashyap.

Imaging Research

ODYSSEY – MRI and Motor/Cognitive Function

Prospective Evaluation of Potential Effects of Repeated Gadolinium-Based Contrast Agent (GBCA) Administrations of the Same GBCA on Motor and Cognitive Functions in Neurologically Normal Adults in Comparison to a non-GBCA Exposed Control Group

For more information please contact Teresa at 309-672-4808. The Principal Investigator for this study is Dr. Matthew Kuhn.