Currently Enrolling Clinical Studies

DIAMOND - Heart Failure

A Multicenter, Double-blind, Placebo-controlled, Randomized Withdrawal, Parallel-Group Study of Patiromer for the Management of Hyperkalemia in Subject Receiving Renin-Angiotensin-Aldosterone System Inhibitor (RAASi) Medications for the Treatment of Heart Failure. 

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

EMPULSE - Heart Failure

A multicentre, randomised, double-blind, 90-day superiority trial to evaluate the effect on clinical benefit, safety and tolerability of once daily oral EMPagliflozin 10 mg compared to placebo, initiated in patients hospitalised for acUte heart faiLure (de novo or decompensated chronic HF) who have been StabilisEd

For more information please contact Debra at 309-672-3194. The Principal Investigator for this study is Dr. Alexander Adler.

NODE - Paroxysmal Supraventricular Tachycardia

Multi-Centre, Multi-National, Open Label, Safety Study of Etripamil Nasal Spray for Patients with Paroxysmal Supraventricular Tachycardia

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Adel Mina.

PARAGLIDE - Heart Failure

A multicenter, randomized, double-blind, double-dummy, parallel group, active controlled 8-week study to evaluate the effect of sacubitril/valsartan (LCZ696) versus valsartan on changes in NT-proBNP and safety and tolerability of in hospital initiation of LCZ696 compared to valsartan in HFpEF patients with acute decompensated heart failure (ADHF) who have been stabilized during hospitalization.

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

SPIRRIT - Heart Failure

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

TRANSFORM - Heart Failure

ToRsemide compArisoN with furoSemide FOR Management of Heart Failure

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. Alexander Adler.

Diabetes Research

ARISE - Diabetic Cardiomyopathy

A Multicenter, Randomized, Placebo-Controlled Study to Evaluate the Safety and Efficacy of AT-001 in Patients with Diabetic Cardiomyopathy / Stage B Heart Failure at High Risk of Progression to Overt Heart Failure (Stage C Heart Failure)

  

For more information please contact Virginia at 309-672-3153. The Principal Investigator for this study is Dr. David Trachtenbarg.

Gastrointestinal Research

RiCoDIFy - C-Difficile

Phase 3, randomized, double-blind, active controlled study to compare the efficacy and safety of ridinilazole (200 mg, bid) for 10 days with vancomycin (125 mg, qid) for 10 days in the treatment of Clostridium difficile infection (CDI).

For more information please contact Amy at 309-672-3118. The Principal Investigator for this study is Dr. David Trachtenbarg.

Oncology Research

SEERPRO - Cancer

A Prospective Blood Sample Collection Study to Evaluate a Panel of Protein-based Biomarkers

 

For more information please contact Debra at 309-672-3194. The Principal Investigator for this study is Dr. Candace Correa.

RESOLUTE – COPD