Clinical Research

Clinical research is a vital component of today's ever-evolving healthcare field, allowing physicians and providers to break new ground and giving patients new alternatives to lifesaving treatment options. UnityPoint Health – Meriter regularly participates in clinical research — giving us the opportunity to test the safety and effectiveness of new treatments such as medicines, medical procedures and devices.

Patients volunteer to participate in clinical research because they hope it will benefit them and because they want to contribute to a research effort that helps patients in the future. Whether the outcome of clinical research is beneficial or disappointing, patients involved in clinical research are helping to find new and better treatments.

If you are interested in learning more about a specific research project, please contact the person listed.

Ear, Nose and Throat 

  • ELLIOT -  A Randomized Clinical Study of Safety of Efficacy for the Eustachian Tube Balloon Catheter.

Heart & Vascular

  • AMGEN 18 - A Double-blind, Randomized, Placebo and Ezetimibe Controlled, Multicenter Study to Evaluate Safety, Tolerability and Efficacy of AMG 145 on LDL-C in Combination With Statin Therapy in Subjects With Primary Hypercholesterole

  • BEST-CLI - Randomized, Multicenter, Controlled Trial to Compare Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia

  • CANTOS - A randomized, double-blind, placebo-controlled, event-driven trial of quarterly subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable post-myocardial patients

  • Clear Outcomes - A randomized, Double-Blind, Placebo-Controlled Study to Access the Effects of Bempedoic Acid (ETC-1002) on the Occurence of Major Cardiovascular Events in Patients with, or at High Risk for Cardiovascular Disease who are Statin Intolerant

  • DECLARE TIMI 58 - Dapagliflozin Effect on Cardiovascular Events

  • EXPRESSGRAFT - An Open-Label, Prospective, Multicenter, Safety, and Tolerability Study of Expressgraft-C9T1 Skin Tissue in the Treatment of Diabetic Foot Ulcers.

  • Galactic-HF - A Double-Blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects with Chronic Heart Failure With Reduced Ejection Fraction.

  • Harmony - A long term, randomized, double-blind, placebo-controlled study to determine the effect of albiglutide, when added to standard bold glucode lowering therapies, on major cardiovascular events in patients with type two diabetes mellitus.

  • LSS 4-Site - The Longitudinal Surveillance Study of the 4-SITE

  • PROMINENT - Pemafibrate to reduce cardiovascular outcomes by reducing triglycerides in diabetes patients. 

  • PROMUS - Element Plus US Post-Approval Study

  • REVEAL - Randomized Evaluation of the Effects of Anacetrapib through Lipid Modification

  • SAFE-DBC - A Prospective, Multicenter, Single Arm, Real-World Registry Assessing the Clinical Use of the Lutonix® 035 Drug Coated Balloon Catheter in Arteries of the Superficial Femoral Artery (SFA) and Popliteal Artery (PA)

  • VOYAGER - Vascular Outcomes study of Asa along with rivaroxaban in Endovascular or surgical limb Revascularization for peripheral artery disease (PAD)

Mental Health 

  • 2016-009 - Use of a "Safe Kit" to Improve Patients' Perceived Self - Efficacy in Regulating Emotions, while Reducing Self-Harming Behaviors 

Swallowing Disorders

  • SwallowSolutions - Development of Biophysically-based Fluids for People with Swallowing Disorders 

Women's Health, including Maternal, Prenatal Health and Newborns

  • 2010-001 - Determining PCOS-like traits in macaques and newborn

  • 2016-005 - Travel During Pregnancy