UnityPoint Health - Des Moines

Contraindications to Transplantation

Absolute Contraindications to Transplantation

  • Active infection
  • Active malignancy
  • Psychosocial contraindications
  • Non-compliance with medical management
  • Active substance abuse

Relative Contraindications to Transplantation

  • Smoking
  • Advanced age combined with poor health status
  • Lack of appropriate social support
  • Multiple system organ failure
  • BMI > 40
  • History of illicit drug use and substance abuse
  • Advanced cardiopulmonary disease
  • Past history of malignancy
  • Active autoimmune disease

Our team accepts patients with higher BMIs, and if indicated, we will refer them to a Medical Weight Loss Program or Bariatric Program to assist them in weight loss, allowing them the opportunity to become a transplant candidate. 

Our psychosocial team will work with patients with a history of non-adherence or substance abuse/mental health issues. We utilize adherence agreements and follow-up to allow them the opportunity to become a transplant candidate. We can help them get set up with a Detox/Rehab Center and utilize random drugs screens. We can also assist with psychiatric evaluation/treatment as indicated.